PCOS supplements have varying evidence. Some have reasonable support for specific aspects (insulin resistance, ovulation). Best supplements for pcos includes options that may help alongside lifestyle and medical treatment. Always discuss with your gynecologist or endocrinologist.
Supplements with evidence
Myo-inositol: Most studied. Improves insulin sensitivity, ovulation. Often combined with D-chiro-inositol in 40:1 ratio. 2-4 g daily.
Vitamin D: Deficiency common in PCOS. Treatment helps metabolic parameters.
Omega-3 fatty acids: Some evidence for metabolic and inflammatory aspects.
NAC: Some evidence for fertility and insulin sensitivity.
Magnesium: If deficient. Common in PCOS.
Lifestyle and medical treatments
More impactful than supplements alone:
- Weight management (5-10% loss often improves symptoms)
- Mediterranean or low-glycemic diet
- Regular exercise
- Metformin (prescription) for insulin resistance
- Hormonal contraceptives for hormonal aspects
- Spironolactone for androgen excess
- Fertility treatments when appropriate
Frequently Asked Questions
What’s the best PCOS supplement?
Myo-inositol has most evidence. Combined with lifestyle changes.
Should I take inositol with metformin?
Possible to combine; some studies show synergistic effects.
How long until inositol works?
3-6 months for menstrual and metabolic improvements.
What about berberine for PCOS?
Some evidence for insulin sensitivity. Less data than metformin.
Will supplements help me get pregnant?
Inositol may improve ovulation. Comprehensive fertility evaluation if struggling.
The bottom line on PCOS supplements
Inositol most evidence. Combined with lifestyle and prescription treatments when appropriate. Discuss with gynecologist or endocrinologist.