Express Scripts Address and Phone Number

Millions of Americans rely on Express Scripts to manage their prescription benefits, yet tracking down the right contact information can feel like navigating a maze. Whether you need the Express Scripts address and phone number for a billing dispute, a lost shipment, or a prior authorization question, the single most important thing to know is this: the contact details that actually apply to you are printed on your prescription ID card, and they vary from plan to plan. This guide explains how to find the right department, why the numbers differ, and where to verify current information — without guessing.

Who Is Express Scripts?

Express Scripts is one of the largest pharmacy benefit managers (PBMs) in the United States. It has been owned by The Cigna Group since 2018 and now operates under Evernorth Health Services, Cigna’s health-services division — you may see it branded as “Express Scripts by Evernorth.” If your employer or health plan uses Express Scripts, the company sits between you, your insurer, and the pharmacy, processing claims, negotiating drug prices, and managing your plan’s formulary.

Understanding what a PBM does can help you ask the right questions when you call. For a deeper look at how these companies operate, see our guide to PBMs or our broader healthcare policy guide. It’s also worth noting that the PBM landscape is changing: Cigna’s Evernorth has announced a move toward a rebate-free reimbursement model for Express Scripts beginning in 2026, along with a simplified member experience. Details roll out over time, which is one more reason to confirm anything time-sensitive on the official site rather than relying on older third-party listings.

Why the “One Phone Number” Answer Doesn’t Exist

It’s tempting to look for a single Express Scripts phone number, but Express Scripts administers benefits for thousands of different employers and health plans, and each plan can route members to its own dedicated service line and hours. That is why the number on the back of your ID card is the one that connects you to the team that actually handles your benefit. A general number you find on a third-party website may reach the wrong queue, may be out of date, or may not apply to your plan at all.

So before you dial, flip your prescription ID card over. You will typically find a member services phone number, and often a separate number for pharmacy or mail-order questions. Medicare Part D members usually have a distinct line printed on their plan materials. If you can’t find your card, log in at express-scripts.com or the Express Scripts mobile app, where the correct contact information for your specific plan is displayed.

Express Scripts Mailing Addresses

Just as with phone numbers, there is no single mailing address that fits every purpose. Express Scripts maintains different destinations for prescriptions and mail-order pharmacy, paper claims and reimbursement, prior authorization, and appeals or grievances — and some employers use regional processing centers. Sending a document to the wrong address can delay processing by weeks.

The company’s corporate headquarters is commonly listed in public records at One Express Way, St. Louis, Missouri. However, the corporate office is not where you should send prescriptions, claim forms, or appeals. For those, use the specific mailing address printed on your ID card, in your plan’s benefit documents, or shown in your online account. If you can’t locate the right address, contact member services (using the number on your card) and ask them to confirm exactly where to send your paperwork before you mail anything, especially anything time-sensitive like an appeal.

How to Reach Express Scripts Online

Phone calls are not your only option, and for routine tasks the digital channels are often faster.

The Express Scripts member portal at express-scripts.com lets you log in to check order status, request refills, view your plan’s formulary, and update payment information. The mobile app mirrors most of these features and adds shipment tracking. For many members, the app handles day-to-day needs without a phone call. Evernorth also maintains a general Contact Us page at evernorth.com that points you to the correct line based on your type of coverage.

If you prefer written communication, the member site includes a secure messaging feature accessible after login. This keeps your personal health information protected, and response times are generally a business day or two.

When to Use a Mailing Address Instead of Calling

Certain situations call for written correspondence rather than a phone call. Formal appeals, grievances, and legal notices generally need to be submitted in writing, and there is usually a specific address (and sometimes a deadline) for each. If you are filing a formal complaint about a coverage denial, sending your letter to the correct appeals address by a trackable method creates a paper trail that can matter if the dispute escalates.

Claim reimbursement forms sometimes need to be mailed too, particularly if you paid out of pocket at a non-network pharmacy and need to submit receipts. Because these destinations differ by plan, confirm the correct address with member services first rather than assuming the corporate office will forward it.

Tips for Getting Through to a Live Representative

Automated phone systems can be a barrier. A few habits help. Call during off-peak hours — early morning on a weekday tends to have shorter waits, while Mondays and the days after holidays are usually busiest. Have your member ID number ready before you dial, since the system will ask for it, and entering it promptly can move you through the queue faster.

If the automated menu doesn’t offer the option you need, pressing “0” or saying “representative” often connects you to a live agent. Be ready to explain your issue concisely, and write your question down beforehand to keep the conversation focused and reduce the chance of being transferred repeatedly. For any billing, coverage, or appeal matter, note the date, the representative’s name, and any reference number you’re given.

How to Tell If Express Scripts Manages Your Benefits

If you’re not sure which PBM handles your prescriptions, the easiest check is your prescription card. Express Scripts cards generally display the Express Scripts (or Evernorth) branding along with routing details such as a BIN and PCN number that your pharmacy uses to process claims. If your card instead shows CVS Caremark or another PBM, your contact details and portal will be different — see our CVS Caremark contact guide for that. When in doubt, your pharmacist can look at your card and tell you which PBM is processing your claims.

Express Scripts and CVS Caremark are two of the largest PBMs in the country, and both offer phone support and online portals. The practical differences for most members come down to your plan’s pharmacy network and mail-order setup, which affect where you fill and what you pay. Medicare members weighing mail-order options may also find our guide to the best mail order pharmacy for Medicare helpful.

Frequently Asked Questions

What is the fastest way to reach Express Scripts customer service?

Use the member services number printed on the back of your prescription ID card, and have your member ID ready. Calling early on a weekday morning typically means shorter hold times. For routine tasks like refills and order tracking, the Express Scripts mobile app or express-scripts.com is often faster than calling at all.

Can I email Express Scripts directly?

Express Scripts does not publish a general customer service email address. Instead, use the secure messaging feature within your online account at express-scripts.com, which protects your personal health information. For general inquiries, the Evernorth Contact Us page can direct you to the right channel for your coverage.

Where do I mail a prescription to Express Scripts?

The mailing address for prescriptions and mail-order pharmacy varies by plan. Check the address printed on your ID card or shown in your online account — do not send prescriptions to the corporate headquarters, as they may not reach the correct processing center. If you’re unsure, call member services and confirm the address first.

Is Express Scripts the same as Evernorth or Cigna?

Express Scripts is the pharmacy benefit manager operated under Evernorth Health Services, which is part of The Cigna Group. You may see the “Express Scripts by Evernorth” name. For most member tasks, you’ll still use the Express Scripts website, app, and the phone number on your card.

Why is the phone number I found online not working for my plan?

Because Express Scripts administers many different employer and health-plan benefits, phone numbers and mailing addresses are plan-specific and can change. A number listed on a third-party site may be outdated or route to a different plan. The number on your current ID card, or the one shown after you log in at express-scripts.com, is the reliable source.

Getting the Help You Need

The most useful Express Scripts address and phone number is the one that matches your plan — and that lives on your ID card and in your online account, not on a generic list. Start with your card for the correct member services line, use the express-scripts.com portal or mobile app for routine tasks like refills and order tracking, and reserve written correspondence for formal appeals or legal matters (to the specific address your plan provides). Keep your member ID handy every time you reach out, document each interaction, and when a detail is time-sensitive, verify it on the official site before you rely on it.

Sources

• Express Scripts by Evernorth — official member site (express-scripts.com) and FAQ (“What is Express Scripts / Evernorth”)
• Evernorth Health Services (evernorth.com) — Contact Us; Express Scripts Pharmacy Benefit Services (2026 simplified member experience)
• The Cigna Group — Evernorth Health Services overview (Express Scripts ownership since 2018)
• General reporting (2025-2026) on Cigna/Express Scripts’ rebate-free pharmacy reimbursement model